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Article

GATA4 loss in the septum transversum mesenchyme promotes liver fibrosis in mice.

Hepatology (Baltimore, Md.) - 1 Jun 2014

Delgado Irene, Carrasco Manuel, Cano Elena, Carmona Rita, García-Carbonero Rocío, Marín-Gómez Luis M, Soria Bernat, Martín Francisco, Cano David A, Muñoz-Chápuli Ramón, Rojas Anabel

Abstract excerpt

UNLABELLED: The zinc finger transcription factor GATA4 controls specification and differentiation of multiple cell types during embryonic development. In mouse embryonic liver, Gata4 is expressed in the endodermal hepatic bud and in the adjacent mesenchyme of the septum transversum. Previous studies have shown that Gata4 inactivation impairs liver formation. However, whether these defects are caused by loss of...

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Identifiers

PMID: 24415412
DOI: 10.1002/hep.27005

Genes

GATA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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