Article
Induction of lethal mutations in experimental tumours after single and fractionated irradiations in vivo.
International journal of radiation biology - 1 Jul 1998
Chatterjee A, Rojas A, Hodgkiss R J
Abstract excerpt
PURPOSE: To investigate the prolonged reduction in cellular viability (lethal mutations) of surviving cells following irradiation of tumours in vivo and to test the effects of fractionation on the expression of lethal mutations. MATERIALS AND METHODS: A mouse mammary carcinoma (CaNT) was treated with single dose or fractionated X-ray treatments in vivo and survival quantified with an in vitro excision assay soon...
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