Article
Contribution of lethal mutations to excision assays for tumour cell survival.
Acta oncologica (Stockholm, Sweden) - 1 Jan 1995
Chatterjee A, Hodgkiss R J, Rojas A
Abstract excerpt
Conventional assays of cell survival determine only the proportion of colony-forming cells, assuming that all such cells are equivalent. However, cells surviving irradiation are reported to have lower plating efficiencies than unirradiated controls, suggesting an additional component of cellular...
Topics
- Animals
- CHO Cells
- Cell Survival
- Cricetinae
- Dose-Response Relationship, Radiation
- Mammary Neoplasms, Experimental
- Mice
- Mutation
- Radiotherapy
- Time Factors