Topoisomerase mutations in trovafloxacin-resistant Staphylococcus aureus.

doi:10.1128/AAC.42.8.2122

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Article

Topoisomerase mutations in trovafloxacin-resistant Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Aug 1998

Fitzgibbon J E, John J F, Delucia J L, Dubin D T

Abstract excerpt

A total of 201 Staphylococcus aureus isolates were surveyed for susceptibility to ciprofloxacin and trovafloxacin. Of 66 methicillin-resistant isolates, 89% were ciprofloxacin resistant and 6% were also trovafloxacin resistant. Trovafloxacin-resistant strains had unusual patterns of quinoline res...

Topics

Anti-Infective Agents
Ciprofloxacin
DNA Topoisomerase IV
DNA Topoisomerases, Type II
Drug Resistance, Microbial
Fluoroquinolones
Humans
Microbial Sensitivity Tests
Mutation
Naphthyridines
Staphylococcus aureus

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