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Genetic Architecture of Reproduction and Longevity in Historical Dutch Cohorts

2026-06-03

Abstract excerpt

Life-history theory predicts a trade-off between reproduction and survival, often invoked to explain human ageing through antagonistic pleiotropy, yet evidence for a genetic trade-off between fertility and longevity in humans remains mixed. We tested whether reproductive traits and lifespan are linked by additive genetic covariance in a large historical Dutch genealogical dataset comprising individuals born betwee...

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Literature Corpus work
a76973a7-8167-58ec-b383-8b4514c4b317
DOI
10.64898/2026.06.02.729506
Open publication

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Genetic Architecture of Reproduction and Longevity in Historical Dutch CohortsDOI 10.64898/2026.06.02.729506
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