Article
Mutation load and human longevity.
Mutation research - 9 Jun 1997
Gavrilov L A, Gavrilova N S, Kroutko V N, Evdokushkina G N, Semyonova V G, Gavrilova A L, Lapshin E V, Evdokushkina N N, Kushnareva Y E
Abstract excerpt
Since paternal age at reproduction is considered to be the main factor determining human spontaneous mutation rate (Crow, J. (1993) Environ. Mol. Mutagenesis, 21, 122-129), the effect of paternal age on human longevity was studied on 8,518 adult persons (at age 30 and above) from European aristoc...
Topics
- Adult
- Aged
- Europe
- Female
- Humans
- Longevity
- Male
- Middle Aged
- Mutation
- Nuclear Family
- Paternal Age
- Reproduction
- Sex Factors
- X Chromosome