Allelic deletion at glutathione S-transferase M1 locus and its association with breast cancer susceptibility.

doi:10.1016/s0009-2797(97)00173-7

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Article

Allelic deletion at glutathione S-transferase M1 locus and its association with breast cancer susceptibility.

Chemico-biological interactions - 24 Apr 1998

Maugard C M, Charrier J, Bignon Y J

Abstract excerpt

Glutathione S-transferases (GSTs) are a family of isoenzymes involved in cellular detoxification. Previous studies have correlated the absence of the GSTM1 protein with an increased risk of developing some cancers, especially lung or bladder cancer, in heavy smokers. In this study, we determined...

Topics

Adult
Age Factors
Aged
Aged, 80 and over
Alleles
Breast Neoplasms
Case-Control Studies
Female
France
Gene Deletion
Gene Frequency
Genotype
Glutathione Transferase
Heterozygote
Homozygote
Humans
Middle Aged

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