Article
Genetic heterogeneity of the structure and function of GSTT2 and GSTP1.
Chemico-biological interactions - 24 Apr 1998
Board P, Harris M, Flanagan J, Langton L, Coggan M
Abstract excerpt
In this study new methods for the detection of two polymorphic sites in the GSTP1 coding region have been developed. Both sites are polymorphic in several racial groups and there are significant differences between groups, in the gene frequency at each site. Although previous studies of recombina...
Topics
- Alleles
- Base Sequence
- Codon, Terminator
- DNA Primers
- Exons
- Gene Frequency
- Genotype
- Glutathione Transferase
- Humans
- Introns
- Isoenzymes
- Multigene Family
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Pseudogenes
- Racial Groups