Article
TATA-box mutant in the promoter of the uridine diphosphate glucuronosyltransferase gene in Italian patients with Gilbert's syndrome.
Italian journal of gastroenterology and hepatology - 1 Apr 1998
Sampietro M, Lupica L, Perrero L, Romano R, Molteni V, Fiorelli G
Abstract excerpt
BACKGROUND: A mutation in the promoter of the uridine diphosphate glucuronosyltransferase gene has been described in patients with Gilbert's syndrome from Northern Europe. AIMS: To assess the frequency of this mutation in Italian patients with Gilbert's syndrome and in normal controls, in order t...
Topics
- Adolescent
- Adult
- Aged
- Base Sequence
- Confidence Intervals
- Female
- Genetic Markers
- Genotype
- Gilbert Disease
- Glucuronosyltransferase
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Sensitivity and Specificity
- TATA Box