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Article

(TA)8 allele in the UGT1A1 gene promoter of a Caucasian with Gilbert's syndrome.

Haematologica - 1 Feb 1999

Iolascon A, Faienza M F, Centra M, Storelli S, Zelante L, Savoia A

Abstract excerpt

BACKGROUND AND OBJECTIVE: Gilbert's syndrome, a chronic non-hemolytic unconjugated hyperbilirubinemia, is caused by a reduction in the activity of hepatic bilirubin UDP-glucuronosyltransferase (UGT1A1). This reduction has been shown to be due to a polymorphism in the promoter region of the UGT1A1 gene. The presence of seven thymine adenine (TA) repeats reduces the efficiency of transcription of the UGT1A1 gene....

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Identifiers

PMID: 10091406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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