Human alpha-adducin gene, blood pressure, and sodium metabolism.

doi:10.1161/01.hyp.32.1.138

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Article

Human alpha-adducin gene, blood pressure, and sodium metabolism.

Hypertension (Dallas, Tex. : 1979) - 1 Jul 1998

Kamitani A, Wong Z Y, Fraser R, Davies D L, Connor J M, Foy C J, Watt G C, Harrap S B

Abstract excerpt

The adducin genes contribute significantly to population variation in rat blood pressure and cell membrane sodium transport. The 460Trp mutation of the human alpha-adducin gene has been associated with hypertension, in particular hypertension sensitive to sodium restriction. We studied the relati...

Topics

Adolescent
Adult
Alleles
Analysis of Variance
Base Sequence
Blood Pressure
Calmodulin-Binding Proteins
Cytoskeletal Proteins
DNA
Erythrocytes
Female
Gene Frequency
Genetic Variation
Genotype
Humans
Male
Middle Aged
Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 9674650
DOI: 10.1161/01.hyp.32.1.138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9674650-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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