Article
Alpha-adducin polymorphism in hypertensives of South African ancestry.
American journal of hypertension - 1 Jun 2000
Barlassina C, Norton G R, Samani N J, Woodwiss A J, Candy G C, Radevski I, Citterio L, Bianchi G, Cusi D
Abstract excerpt
The alpha-adducin gene contributes significantly to hypertension in MHS rats (rats of the Milan hypertensive strain) and in some white and Japanese populations, causing a low renin, sodium, and diuretic-sensitive hypertension. No data are available from populations of African ancestry who have a high prevalence of low renin, sodium, and diuretic-sensitive hypertension. We studied the relationship between the...
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