Alpha-adducin polymorphism in hypertensives of South African ancestry.

doi:10.1016/s0895-7061(00)01187-0

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Article

Alpha-adducin polymorphism in hypertensives of South African ancestry.

American journal of hypertension - 1 Jun 2000

Barlassina C, Norton G R, Samani N J, Woodwiss A J, Candy G C, Radevski I, Citterio L, Bianchi G, Cusi D

Abstract excerpt

The alpha-adducin gene contributes significantly to hypertension in MHS rats (rats of the Milan hypertensive strain) and in some white and Japanese populations, causing a low renin, sodium, and diuretic-sensitive hypertension. No data are available from populations of African ancestry who have a high prevalence of low renin, sodium, and diuretic-sensitive hypertension. We studied the relationship between the...

Topics

Adult
Alleles
Blood Pressure
Calmodulin-Binding Proteins
Cytoskeletal Proteins
DNA
DNA Primers
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Hypertension
Male

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Point Mutation

Polymerase Chain Reaction

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 10912759
DOI: 10.1016/s0895-7061(00)01187-0

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