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Specificity of mouse and human Fcgamma receptors and their polymorphic variants for IgG subclasses of different species

8 Feb 2022

Abstract excerpt

IgG is the predominant antibody class generated during infections and used for the generation of therapeutic antibodies. Antibodies are mainly characterized in or generated from animal models that support particular infections, respond to particular antigens or allow the generation of hybridomas. Due to the availability of numerous transgenic mouse models and the ease of performing bioassays with human blood...

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PMID: 35133670
DOI: 10.1002/eji.202149766

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