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Article

Immune response in the hamster: definition of a novel IgG not expressed in all hamster strains.

Immunology - 1 Sept 1995

Coe J E, Schell R F, Ross M J

Abstract excerpt

A new IgG isotype is described in serum from Syrian hamsters. This 7S-IgG is called IgG3 and was isolated from IgG1 and IgG2 because of its great affinity for protein A. The unique antigenic determinants of IgG3 were identified with a specific rabbit antisera. IgG3 is the least expressed IgG subclass in Syrian hamsters, but serum levels increase more than 10-fold after immunization or infection. Although found in...

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Identifiers

PMID: 7590875
PMCID: PMC1383822

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