Article
New TAP2 polymorphisms in Africans.
Tissue antigens - 1 May 1998
Tang J, Allen S, Karita E, Musonda R, Kaslow R A
Abstract excerpt
Polymorphisms in genes encoding transporters associated with antigen processing (TAP) have been associated with heterogeneity of disease progression in HIV-1-infected homosexual men. In our recent AIDS-related studies of cohorts from Rwanda and Zambia, four new polymorphic sites in the TAP2 coding region were detected by single-strand conformation polymorphism (SSCP) and confirmed by bi-directional nucleotide...
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