Article
Novel TAP1 polymorphisms in indigenous Zimbabweans: their potential implications on TAP function and in human diseases.
Human immunology - 1 Aug 2003
Lajoie Julie, Zijenah Lynn S, Faucher Marie Claude, Ward Brian J, Roger Michel
Abstract excerpt
Because of the essential role of transporter associated with antigen processing (TAP1 or TAP2) molecule in antigen processing, the implication of its polymorphism as a factor involved in human diseases and the possible genetic variation at this locus among ethnically diverse populations, we underwent a study to analyze the full extent of TAP1 polymorphism in an indigenous Zimbabwean population (Shona ethnic...
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