Article
TAPI polymorphisms in several human ethnic groups: characteristics, evolution, and genotyping strategies.
Human immunology - 1 Mar 2001
Tang J, Freedman D O, Allen S, Karita E, Musonda R, Braga C, Margolick J, Kaslow R A
Abstract excerpt
Genetic variations in the locus encoding the transporter associated with antigen processing, subunit 1 (TAP1), were systematically studied using samples from Caucasians, Africans, Brazilians, and compared with data from chimpanzees. PCR-amplified genomic sequences corresponding to the 11 exons were analyzed by single-strand conformation polymorphism (SSCP) and sequencing. Six nonsynonymous and 2 synonymous single...
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