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Article

Genetic diversity of the alpha-1-antitrypsin gene in Africans identified using a novel genotyping assay.

Human mutation - 1 Jul 2003

Hayes Vanessa M

Abstract excerpt

The highly polymorphic human alpha-1-antitrypsin (AAT) gene, more recently named SERPINA1, codes for the most abundant circulating plasma serine protease inhibitor, protease inhibitor 1 (PI). Most studies determining AAT haplotype frequencies have been restricted first by the limited accuracy of the phenotypic method used and secondly by the analysis of predominantly Caucasian populations. Limited studies have...

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Identifiers

PMID: 12815594
DOI: 10.1002/humu.10231

Genes

SERPINA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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