Article
Analysis of transporter associated with antigen presentation (TAP) genes polymorphisms with HIV-1 infection.
Molecular and cellular biochemistry - 1 Jan 2020
Abitew Abaineh Munshea, Sobti Ranbir Chander, Sharma Vijay Lakshmi, Wanchu Ajay
Abstract excerpt
Human leukocyte antigen (HLA) class I molecules of the human major histocompatibility complex (MHC) play an important role in modulating immune response. HLA class I molecules present antigenic peptides to CD8+ T cells and thereby play a role in the immune surveillance of cells infected with viruses. TAP1 and TAP2 are MHC-II-encoded genes necessary for the generation of a cellular immune response and polymorphism...
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