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Article

Highly accurate analysis of heterozygous loci bysingle cell PCR.

Nucleic acids research - 1 Aug 1998

Garvin A M, Holzgreve W, Hahn S

Abstract excerpt

Single cell PCR is a powerful method for determining the genetic properties of individual cells. In the instance of heterozygous loci, however, preferential amplification of one allele can lead to allele drop out (ADO) of the other allele. Fortunately ADO does not occur in all amplifications, and is usually random when it does occur, with both alleles being equally susceptible to drop out. Therefore pooling of...

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Identifiers

PMID: 9671806
DOI: 10.1093/nar/26.15.3468
PMCID: PMC147732

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ADO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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