Telomere length regulation in mice is linked to a novel chromosome locus

Abstract excerpt

Little is known about the mechanisms that regulate species-specific telomere length, particularly in mammalian species. The genetic regulation of telomere length was therefore investigated by using two inter-fertile species of mice, which differ in their telomere length. Mus musculus (telomere length >25 kb) and Mus spretus (telomere length 5-15 kb) were used to generate F1 crosses and reciprocal backcrosses,...

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• Share to Chromosomal and Genetic Variations
• Share to Genetics, Aging, and Longevity in Model Organisms
• Share to Telomeres, Telomerase, and Senescence