Article
Genetic dissection of X-linked interspecific hybrid placental dysplasia in congenic mouse strains.
Genetics - 1 Sept 1999
Hemberger M C, Pearsall R S, Zechner U, Orth A, Otto S, Rüschendorf F, Fundele R, Elliott R
Abstract excerpt
Interspecific hybridization in the genus Mus results in male sterility and X-linked placental dysplasia. We have generated several congenic laboratory mouse lines (Mus musculus) in which different parts of the maternal X chromosome were derived from M. spretus. A strict positive correlation between placental weight and length of the M. spretus-derived part of the X chromosome was shown. Detailed analysis was...
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