Article
Replication analysis of a putative susceptibility locus (EGI) for idiopathic generalized epilepsy on chromosome 8q24.
Epilepsia - 1 Jul 1998
Sander T, Kretz R, Schulz H, Sailer U, Bauer G, Scaramelli A, Epplen J T, Riess O, Janz D
Abstract excerpt
PURPOSE: The present replication study was designed to test the validity of a previously mapped susceptibility locus (EGI) for common subtypes of idiopathic generalized epilepsy (IGE) in chromosomal region 8q24. METHODS: Thirty-eight multiplex families of probands with common IGE syndromes were i...
Topics
- Chromosome Mapping
- Chromosomes, Human, Pair 8
- Electroencephalography
- Epilepsies, Myoclonic
- Epilepsy, Generalized
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Lod Score
- Microsatellite Repeats
- Models, Genetic
- Polymorphism, Genetic
- Reproducibility of Results