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Article

No evidence for a susceptibility locus for idiopathic generalized epilepsy on chromosome 18q21.1.

American journal of medical genetics - 8 Aug 2002

Sander Thomas, Windemuth Christine, Schulz Herbert, Saar Kathrin, Gennaro Elena, Bianchi Amedeo, Zara Federico, Bulteau Christine, Kaminska Anna, Ville Dorothée, Cieuta Cécile, Prud'homme Jean-François, Dulac Olivier, Bate Louise, Gardiner R Mark, de Haan Gerrit-Jan, Janssen Guus A M A J, Witte Jorine, Halley Dicky J J, Lindhout Dick, Wienker Thomas F, Janz Dieter

Abstract excerpt

A recent genome-wide scan showed strong evidence for a major locus for common syndromes of idiopathic generalized epilepsy (IGE) at the marker D18S474 on chromosome 18q21.1 (LOD score 4.5/5.2 multipoint/two-point). The present replication study tested the presence of an IGE locus in the chromosomal region 18q21.1. Our linkage study included 130 multiplex families of probands with common IGE syndromes. Eleven...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12210286
DOI: 10.1002/ajmg.10645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No evidence for a susceptibility locus for idiopathic generalized epilepsy on chromosome 18q21.1.PMID 12210286Read ↗

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