Article
Genetic architecture of idiopathic generalized epilepsy: clinical genetic analysis of 55 multiplex families.
Epilepsia - 1 May 2004
Marini Carla, Scheffer Ingrid E, Crossland Kathryn M, Grinton Bronwyn E, Phillips Fiona L, McMahon Jacinta M, Turner Samantha J, Dean Joanne T, Kivity Sara, Mazarib Aziz, Neufeld Miriam Y, Korczyn Amos D, Harkin Louise A, Dibbens Leanne M, Wallace Robyn H, Mulley John C, Berkovic Samuel F
Abstract excerpt
PURPOSE: In families with idiopathic generalized epilepsy (IGE), multiple IGE subsyndromes may occur. We performed a genetic study of IGE families to clarify the genetic relation of the IGE subsyndromes and to improve understanding of the mode(s) of inheritance. METHODS: Clinical and genealogic data were obtained on probands with IGE and family members with a history of seizures. Families were grouped according...
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