Exploration of the genetic architecture of idiopathic generalized epilepsies.

doi:10.1111/j.1528-1167.2006.00677.x

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Article

Exploration of the genetic architecture of idiopathic generalized epilepsies.

Epilepsia - 1 Oct 2006

Hempelmann Anne, Taylor Kirsten P, Heils Armin, Lorenz Susanne, Prud'homme Jean-Francois, Nabbout Rima, Dulac Olivier, Rudolf Gabrielle, Zara Federico, Bianchi Amedeo, Robinson Robert, Gardiner R Mark, Covanis Athanasios, Lindhout Dick, Stephani Ulrich, Elger Christian E, Weber Yvonne G, Lerche Holger, Nürnberg Peter, Kron Katherine L, Scheffer Ingrid E, Mulley John C, Berkovic Samuel F, Sander Thomas

Abstract excerpt

PURPOSE: Idiopathic generalized epilepsy (IGE) accounts for approximately 20% of all epilepsies and affects about 0.2% of the general population. The etiology of IGE is genetically determined, but the complex pattern of inheritance suggests an involvement of a large number of susceptibility genes. The objective of the present study was to explore the genetic architecture of common IGE syndromes and to dissect out...

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PMID: 17054691
DOI: 10.1111/j.1528-1167.2006.00677.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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