Article
Positive regulation of the human macrophage stimulating protein gene transcription. Identification of a new hepatocyte nuclear factor-4 (HNF-4) binding element and evidence that indicates direct association between NF-Y and HNF-4.
The Journal of biological chemistry - 24 Jul 1998
Ueda A, Takeshita F, Yamashiro S, Yoshimura T
Abstract excerpt
We previously reported that the transcription of the human macrophage stimulating protein (MSP) gene was positively regulated by the binding of NF-Y to the CAATT sequence in the promoter region of this gene. Here we confirmed our previous results and further characterized the MSP promoter. Lucife...
Topics
- Base Sequence
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Binding Sites
- CCAAT-Enhancer-Binding Proteins
- DNA-Binding Proteins
- Gene Expression Regulation
- Growth Substances
- HeLa Cells
- Hepatocyte Growth Factor
- Hepatocyte Nuclear Factor 4
- Humans
- Molecular Sequence Data