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Article

The repressive function of AP2 transcription factor on the hepatocyte growth factor gene promoter.

Biochemical and biophysical research communications - 16 Jun 2000

Jiang J G, DeFrances M C, Machen J, Johnson C, Zarnegar R

Abstract excerpt

Hepatocyte growth factor is an important multifunctional growth factor whose gene expression is tightly regulated at the transcriptional level. Previous studies from our laboratory have shown that several cis-acting elements are present in the promoter and proximal promoter region of the HGF gene. In this study, we have uncovered that AP2 transcription factor specifically binds to a regulatory site located at...

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Identifiers

PMID: 10860846
DOI: 10.1006/bbrc.2000.2848

Genes

HGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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