Article
Pre-mRNA trans-splicing: from kinetoplastids to mammals, an easy language for life diversity.
Memorias do Instituto Oswaldo Cruz - 1 Aug 2005
Mayer Mario Gustavo, Floeter-Winter Lucile Maria
Abstract excerpt
Since the discovery that genes are split into intron and exons, the studies of the mechanisms involved in splicing pointed to presence of consensus signals in an attempt to generalize the process for all living cells. However, as discussed in the present review, splicing is a theme full of variations. The trans-splicing of pre-mRNAs, the joining of exons from distinct transcripts, is one of these variations with...
Topics
- Animals
- Gene Expression Regulation
- Genetic Variation
- Kinetoplastida
- Mammals
- Nematoda
- Phylogeny
- RNA Precursors
- Trans-Splicing
