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Article

Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk.

1 Jul 1998

Abstract excerpt

PURPOSE: Previous studies of mutations in BRCA1 or BRCA2 have used detection methods that may underestimate the actual frequency of mutations and have analyzed women using heterogeneous criteria for risk of hereditary cancer. PATIENTS AND METHODS: A total of 238 women with breast cancer before age 50 or ovarian cancer at any age and at least one first- or second-degree relative with either diagnosis underwent...

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Identifiers

PMID: 9667259
DOI: 10.1200/jco.1998.16.7.2417

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