Article
Genetic polymorphisms of factor VII are not associated with arterial thrombosis.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Apr 1998
Corral J, González-Conejero R, Lozano M L, Rivera J, Vicente V
Abstract excerpt
A high plasma concentration of factor VII procoagulant activity is considered an independent risk factor for coronary heart disease. Recently, two polymorphisms of factor VII gene (insertion of a decanucleotide at -323 [A2], and the variant Q353) have been associated with 20-25% lower levels of t...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Cerebrovascular Disorders
- Coronary Thrombosis
- DNA Mutational Analysis
- Diabetes Mellitus
- Disease Susceptibility
- Factor VII
- Female
- Genotype
- Humans
- Hypercholesterolemia
- Hypertension
- Male
- Middle Aged
- Mutagenesis, Insertional