Article
Lack of association between potential prothrombotic genetic risk factors and arterial and venous thrombosis.
Genetics and molecular research : GMR - 14 Aug 2015
Evangelista F C G, Rios D R A, Ribeiro D D, Carvalho M G, Dusse L M S, Fernandes A P, Sabino A P
Abstract excerpt
Recent studies have shown an association between thrombosis and factor VII (FVII), tissue factor (TF), and angiotensin-converting enzyme (ACE). This suggests that individuals with FVII-402 G/A, FVII-401 G/T, TF+5466 A/G, and ACE-287 insertion/deletion (I/D) polymorphisms present an increased risk of venous thrombosis, heart disease, and ischemic stroke compared with controls. In this study, we investigated the...
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