Article
The decanucleotide polymorphism in the factor VII promoter predicts factor VII plasma levels but not the risk of acute coronary syndromes.
Journal of thrombosis and thrombolysis - 1 Aug 2000
Jimenez-Boj E, Schüttrumpf J, Forberg E, Watzke H H, Huber K
Abstract excerpt
It is known from large epidemiological studies that the elevation of coagulation factor VII in plasma is an independent risk factor for acute coronary syndromes. The level of factor VII is influenced by polymorphic sites in the factor VII gene. However, data on the association of such polymorphisms with the risk of acute coronary syndromes are conflicting. A decanucleotide insertion/deletion polymorphic site has...
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