The effect of stromal cell-derived factor 1 (SDF1/CXCL12) genetic polymorphism on HIV-1 disease progression.

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Article

The effect of stromal cell-derived factor 1 (SDF1/CXCL12) genetic polymorphism on HIV-1 disease progression.

International journal of molecular medicine - 1 Oct 2006

Reiche Edna Maria Vissoci, Ehara Watanabe Maria Angelica, Bonametti Ana Maria, Kaminami Morimoto Helena, Akira Morimoto Arilson, Wiechmann Susana Lilian, Breganó Jose Wander, Matsuo Tiemi, Vissoci Reiche Fernando, Miranda Helen Cristina, Brajão Oliveira Karen, Vogler Ingridt Hildegard, Siscar Alexandra Regina

Abstract excerpt

The human immunodeficiency virus type 1 (HIV-1) epidemic is increasing in Brazil, and little information has been reported about the genetic host factors related to HIV-1 infection in the Brazilian population. A polymorphism in the conserved 3' untranslated region of the stromal cell-derived factor 1 (SDF1/CXCL12) gene has been related either to resistance to HIV-1 infection and delayed progression to AIDS or to...

Topics

Adolescent
Adult
Aged
Alleles
Analysis of Variance
Brazil
CD4 Lymphocyte Count
Chemokine CXCL12
Chemokines, CXC

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Disease Progression

Female

Gene Frequency

Genotype

HIV Infections

HIV-1

Humans

Male

Middle Aged

Source

Open in PubMed

Identifiers

PMID: 16964435

Genes

CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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