Article
Plasma stromal cell-derived factor (SDF)-1 levels, SDF1-3'A genotype, and expression of CXCR4 on T lymphocytes: their impact on resistance to human immunodeficiency virus type 1 infection and its progression.
The Journal of infectious diseases - 1 Oct 2002
Soriano Alex, Martínez Catalina, García Felipe, Plana Montserrat, Palou Eduard, Lejeune Marylène, Aróstegui Juan I, De Lazzari Elisa, Rodriguez Carmen, Barrasa Alicia, Lorenzo José I, Alcamí José, del Romero Jorge, Miró José M, Gatell José M, Gallart Teresa
Abstract excerpt
Plasma stromal cell-derived factor (SDF)-1 levels, SDF1-3'A polymorphism, and CXCR4(+) T lymphocytes in relation to resistance to human immunodeficiency virus (HIV)-1 infection and its progression were investigated in a study of HIV-positive patients, exposed but uninfected (EU) subjects, and healthy control subjects, all lacking CCR5 Delta 32 homozygosity. SDF1-3'A homozygosity was associated with low plasma...
Topics
- Adult
- Chemokine CXCL12
- Chemokines, CXC
- Disease Progression
- Female
- Genotype
- HIV Infections
- HIV Long-Term Survivors
- HIV Seropositivity