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Article

Cefepime-aztreonam: a unique double beta-lactam combination for Pseudomonas aeruginosa.

Antimicrobial agents and chemotherapy - 1 Jul 1998

Lister P D, Sanders W E, Sanders C C

Abstract excerpt

An in vitro pharmacokinetic model was used to determine if aztreonam could enhance the pharmacodynamics of cefepime or ceftazidime against an isogenic panel of Pseudomonas aeruginosa 164, including wild-type (WT), partially derepressed (PD), and fully derepressed (FD) phenotypes. Logarithmic-phase cultures were exposed to peak concentrations achieved in serum with 1- or 2-g intravenous doses, elimination...

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Identifiers

PMID: 9660993
DOI: 10.1128/AAC.42.7.1610
PMCID: PMC105655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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