Article
Cefepime-aztreonam: a unique double beta-lactam combination for Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy - 1 Jul 1998
Lister P D, Sanders W E, Sanders C C
Abstract excerpt
An in vitro pharmacokinetic model was used to determine if aztreonam could enhance the pharmacodynamics of cefepime or ceftazidime against an isogenic panel of Pseudomonas aeruginosa 164, including wild-type (WT), partially derepressed (PD), and fully derepressed (FD) phenotypes. Logarithmic-phas...
Topics
- Aztreonam
- Cefepime
- Cephalosporinase
- Cephalosporins
- Drug Therapy, Combination
- Microbial Sensitivity Tests
- Monobactams
- Mutation
- Pseudomonas aeruginosa