Article
[Evaluation of bactericidal activity of cefpirome-aminoglycoside combination against Pseudomonas aeruginosa strains with intermediate sensitivity to cefpirome and in various phenotypes of beta-lactam resistance].
Pathologie-biologie - 1 May 1997
Canis F, Cavallo J D, Husson M O
Abstract excerpt
The bactericidal activity of cefpirome (CPO)-aminoglycoside (AG) combination was assessed by a kinetic time-kill method against 8 strains of Pseudomonas aeruginosa showing intermediate susceptibility to cefpirome (MICS: 8-32 mg/l). Six strains had an acquired beta-lactam resistance mechanism (mod...
Topics
- Amikacin
- Anti-Bacterial Agents
- Cephalosporins
- Drug Resistance, Microbial
- Drug Therapy, Combination
- In Vitro Techniques
- Microbial Sensitivity Tests
- Phenotype
- Pseudomonas aeruginosa
- Tobramycin
- Cefpirome