Article
The common mutations in the lipoprotein lipase gene in Italy: effects on plasma lipids and angiographically assessed coronary atherosclerosis.
Clinical genetics - 1 Nov 2000
Arca M, Campagna F, Montali A, Barillà F, Mangieri E, Tanzilli G, Seccareccia F, Campa P P, Ricci G, Pannitteri G
Abstract excerpt
The present study evaluated the role of the common lipoprotein lipase (LPL) mutations on the risk of dyslipidemia and coronary atherosclerosis in an Italian population. Cohorts of 632 patients undergoing coronary angiography, as well as 191 healthy controls, were screened by a combination of PCR and restriction enzyme digestion. In the pooled population, the frequencies of LPL D9N and N291S were 4.1%, with no...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.