The murine Dax-1 promoter is stimulated by SF-1 (steroidogenic factor-1) and inhibited by COUP-TF (chicken ovalbumin upstream promoter-transcription factor) via a composite nuclear receptor-regulatory element.

doi:10.1210/mend.12.7.0131

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Article

The murine Dax-1 promoter is stimulated by SF-1 (steroidogenic factor-1) and inhibited by COUP-TF (chicken ovalbumin upstream promoter-transcription factor) via a composite nuclear receptor-regulatory element.

Molecular endocrinology (Baltimore, Md.) - 1 Jul 1998

Yu R N, Ito M, Jameson J L

Abstract excerpt

The Dax-1 gene encodes a protein that is structurally related to members of the orphan nuclear receptor superfamily. Dax-1 is coexpressed with another orphan nuclear receptor, steroidogenic factor-1 (SF-1), in the adrenal, gonads, hypothalamus, and pituitary gland. Mutations in Dax-1 cause adrena...

Topics

Animals
Base Sequence
Binding Sites
COUP Transcription Factor I
Cell Line
Cell Nucleus
Choriocarcinoma
DAX-1 Orphan Nuclear Receptor
DNA
DNA-Binding Proteins
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fushi Tarazu Transcription Factors

Homeodomain Proteins

Humans

Mice

Molecular Sequence Data

Mutation

Placenta

Source

Open in PubMed

Identifiers

PMID: 9658405
DOI: 10.1210/mend.12.7.0131

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9658405-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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