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Reduced expression of syndecan‐1 in human hepatocellular carcinoma with high metastatic potential

21 Oct 1997

Abstract excerpt

Syndecans comprise a gene family of transmembrane proteoglycans that regulate cellular behavior through interactions with various effectors, including heparin-binding growth factors and insoluble matrix components. Syndecan-1, the most extensively studied, localizes in epithelial cells and has been shown to present in normal hepatocytes. However, little is known about the change of syndecan-1 expression in human...

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PMID: 9355969
DOI: 10.1002/(sici)1097-0215(19971021)74:5<482::aid-ijc2>3.0.co;2-#

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