Article
[Phenotype and reactivity of T-lymphocytes isolated from atheromatous plaque. Knowledge obtained from a transplant case].
Archivos del Instituto de Cardiologia de Mexico - 1 Jan 2000
Ramírez T, Rodríguez E, Ruiz V, Collados M R, Massó F, Montaño L F
Abstract excerpt
The primary immunologic hypothesis assumes that the initial damage in atherosclerotic lesions is mediated by T lymphocytes reactive to heat shock proteins, lipoproteins, bacteria, virus or even donor MHC antigens. A frequent cause of heart transplant failure is the de novo formation of atheromatous lesions in the vessels of the transplanted organ despite their absence in the donor, thus suggesting that new...
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