Article
Functional and molecular characterization of graft-infiltrating T lymphocytes propagated from different biopsies derived from one heart transplant patient.
Transplantation - 15 Apr 1994
Datema G, Vaessen L M, Daane R C, Baan C C, Weimar W, Claas F H, van den Elsen P J
Abstract excerpt
Alloreactive T lymphocytes play an important role in graft rejection. In the present study, we have analyzed the cytolytic capacity against donor cells of graft infiltrating T lymphocyte cell lines, which were propagated from various endomyocardial biopsies taken at different time points after transplantation, including during a rejection crisis. Also, T cell clones were generated from the rejection biopsy and...
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