Article
Functional and molecular characterization of graft-infiltrating T lymphocytes propagated from different biopsies derived from one heart transplant patient.
Transplantation - 15 Apr 1994
Datema G, Vaessen L M, Daane R C, Baan C C, Weimar W, Claas F H, van den Elsen P J
Abstract excerpt
Alloreactive T lymphocytes play an important role in graft rejection. In the present study, we have analyzed the cytolytic capacity against donor cells of graft infiltrating T lymphocyte cell lines, which were propagated from various endomyocardial biopsies taken at different time points after tr...
Topics
- Base Sequence
- Biopsy
- CD4-CD8 Ratio
- Cell Line
- Clone Cells
- Graft Rejection
- Heart Transplantation
- Humans
- Immunoglobulin Variable Region
- Molecular Sequence Data
- Phenotype
- Polymerase Chain Reaction
- Receptors, Antigen, T-Cell, alpha-beta
- T-Lymphocytes