Article
Long-range correlations of serial FEV1 measurements in emphysematous patients and normal subjects.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Jul 1998
Dirksen A, Holstein-Rathlou N H, Madsen F, Skovgaard L T, Ulrik C S, Heckscher T, Kok-Jensen A
Abstract excerpt
In obstructive lung disease the annual change in lung function is usually estimated from serial measurements of forced expiratory volume in 1 s (FEV1). Frequent measurements in each patient may not improve this estimate because data are not statistically independent; i.e., the measurements are autocorrelated. The purpose of this study was to describe the correlation structure in time series of FEV1 measurements....
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