[Biochemistry of presenilin 1].

Article

[Biochemistry of presenilin 1].

Rinsho shinkeigaku = Clinical neurology - 1 Dec 1997

Takashima A

Abstract excerpt

The majority of cases of early-onset familial Alzheimer disease are caused by mutations in the recently identified presenilin 1 (PS 1) gene, located on chromosome 14. PS1, a 467 amino acid protein, is predicted to be an integral membrane protein containing seven putative transmembrane domains and...

Topics

Alzheimer Disease
Humans
Membrane Proteins
Mutation
Presenilin-1

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