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Article

Algorithmic approach to high-throughput molecular screening for alpha interferon-resistant genotypes in hepatitis C patients.

Journal of clinical microbiology - 1 Jul 1998

Sreevatsan S, Bookout J B, Ringpis F M, Pottathil M R, Marshall D J, De Arruda M, Murvine C, Fors L, Pottathil R M, Barathur R R

Abstract excerpt

This study was designed to analyze the feasibility and validity of using Cleavase Fragment Length Polymorphism (CFLP) analysis as an alternative to DNA sequencing for high-throughput screening of hepatitis C virus (HCV) genotypes in a high-volume molecular pathology laboratory setting. By using a 244-bp amplicon from the 5' untranslated region of the HCV genome, 61 clinical samples received for HCV reverse...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 9650932
DOI: 10.1128/JCM.36.7.1895-1901.1998
PMCID: PMC104948

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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