Article
A novel hepatitis C virus genotyping method based on liquid microarray.
PloS one - 20 Sept 2010
Duarte Cesar A B, Foti Leonardo, Nakatani Sueli M, Riediger Irina N, Poersch Celina O, Pavoni Daniela P, Krieger Marco A
Abstract excerpt
The strategy used to treat HCV infection depends on the genotype involved. An accurate and reliable genotyping method is therefore of paramount importance. We describe here, for the first time, the use of a liquid microarray for HCV genotyping. This liquid microarray is based on the 5'UTR - the most highly conserved region of HCV - and the variable region NS5B sequence. The simultaneous genotyping of two regions...
Topics
- 5' Untranslated Regions
- Genotype
- Hepacivirus
- Hepatitis C
- Humans
- Microarray Analysis
- Molecular Sequence Data
- Sensitivity and Specificity
- Viral Nonstructural Proteins