Article
Analysis of hepatitis C virus genotypes by a line probe assay and correlation with antibody profiles.
Journal of hepatology - 1 Jul 1994
van Doorn L J, Kleter B, Stuyver L, Maertens G, Brouwer H, Schalm S, Heijtink R, Quint W
Abstract excerpt
The 5' untranslated regions derived from 54 patients with a chronic hepatitis C virus infection were analyzed to determine the (sub)type of hepatitis C virus. Labelled polymerase chain reaction products from 5' untranslated region were used as probes for reverse hybridization in a line probe assay (Inno-LiPA) and results were validated by comparison with direct sequencing data. Five different genotypes could be...
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