Article
Dideoxy fingerprinting for rapid screening of rpoB gene mutations in clinical isolates of Mycobacterium tuberculosis.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Jun 1998
Liu Y C, Huang T S, Huang W K, Chen C S, Tu H Z
Abstract excerpt
Rifampin is a key component of therapeutic regimens for tuberculosis control, and a marker for multidrug resistance of Mycobacterium tuberculosis. Mutations responsible for conferring rifampin resistance in M. tuberculosis are known to occur in a 69-bp region of the rpoB gene. In this study, we assessed the accuracy of dideoxy fingerprinting (ddF), a hybrid technique employing elements of dideoxy sequencing and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
