Dideoxy fingerprinting for rapid screening of rpoB gene mutations in clinical isolates of Mycobacterium tuberculosis.

Article

Dideoxy fingerprinting for rapid screening of rpoB gene mutations in clinical isolates of Mycobacterium tuberculosis.

Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Jun 1998

Liu Y C, Huang T S, Huang W K, Chen C S, Tu H Z

Abstract excerpt

Rifampin is a key component of therapeutic regimens for tuberculosis control, and a marker for multidrug resistance of Mycobacterium tuberculosis. Mutations responsible for conferring rifampin resistance in M. tuberculosis are known to occur in a 69-bp region of the rpoB gene. In this study, we a...

Topics

DNA Fingerprinting
DNA-Directed RNA Polymerases
Humans
Mutation
Mycobacterium tuberculosis
Plant Proteins
Rifampin

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