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Article

Detection of rpoB mutations in Mycobacterium tuberculosis by biprobe analysis.

Journal of clinical microbiology - 1 Sept 2001

Edwards K J, Metherell L A, Yates M, Saunders N A

Abstract excerpt

A biprobe assay utilizing LightCycler technology was developed to detect rifampin resistance-associated gene mutations in the Mycobacterium tuberculosis rpoB gene. Three biprobes detected all mutations present in the 46 rifampin-resistant isolates. Wild-type sequences were correctly identified in each case. The method was reproducible, accurate, and easy to use.

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11526175
DOI: 10.1128/JCM.39.9.3350-3352.2001
PMCID: PMC88343

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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