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Article

Phenotypic analysis of EcR-A mutants suggests that EcR isoforms have unique functions during Drosophila development.

Developmental biology - 15 Jun 2005

Davis Melissa B, Carney Ginger E, Robertson Anne E, Bender Michael

Abstract excerpt

The steroid hormone ecdysone triggers transitions between developmental stages in Drosophila by acting through a heterodimer consisting of the EcR and USP nuclear receptors. The EcR gene encodes three protein isoforms (EcR-A, EcR-B1, and EcR-B2) that have unique amino termini but that contain a common carboxy-terminal region including DNA-binding and ligand-binding domains. EcR-A and EcR-B1 are expressed in a...

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Identifiers

PMID: 15950604
DOI: 10.1016/j.ydbio.2005.03.019
PMCID: PMC3307594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Phenotypic analysis of EcR-A mutants suggests that EcR isoforms have unique functions during Drosophila development.PMID 15950604Read ↗

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